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Results sorted by posted date (newest first)
Posted 3/16/2022 (updated 3/27/2024)
Background: Sharp exacerbations of the US overdose crisis are linked to polysubstance use of synthetic compounds. Xylazine is a veterinary tranquilizer, long noted in the street opioid supply of Puerto Rico, and more recently Philadelphia. Yet its national trends, geographic distribution, and health risks are poorly characterized. Methods: In this sequential mixed-methods study, xylazine was increasingly observed by ethnographers in Philadelphia among drug-sellers and people who inject drugs (PWID). Subsequently, we systematically searched for records describing xylazine-present overdose mortality across the US and assessed time trends and overlap with other drugs
Posted 11/19/2019 (updated 3/25/2024)
The document provides guidance on how to plan for an outbreak of HIV or HCV among PWID including considerations for developing an outbreak response plan to minimize the impact of the outbreak on the community and stop further transmission. The document also outlines strategies to detect and investigate a possible outbreak.